GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9457247 | 1 | rs430097 | chr6:167405073 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs430293 | chr6:167404958 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs430477 | chr6:167389851 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs10935120 | 1 | rs4309773 | chr3:134277301 | ANAPC13 | chr3:134196547-134204865:- | 0.58 | 8.01 | 2.88E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs4309773 | chr3:134277301 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 6.04 | 2.93E-8 | Height |
| THYM | cis | rs2243480 | 1 | rs431076 | chr7:65600320 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.31 | 7.1E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs431318 | chr7:65511597 | CCT6P1 | chr7:65216092-65228661:+ | 0.67 | 5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs10461617 | 1 | rs43184 | chr5:56141777 | C5orf35 | chr5:56205103-56213010:+ | 0.75 | 9.04 | 1.84E-14 | Type 2 diabetes |
| THYM | cis | rs881375 | 1 | rs4323544 | chr9:123647377 | LOC253039 | chr9:123605320-123616644:+ | -0.62 | -5.56 | 2.51E-7 | Rheumatoid arthritis |
| THYM | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.27 | 4.62E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs10935120 | 1 | rs4334685 | chr3:134304335 | ANAPC13 | chr3:134196547-134204865:- | 0.55 | 7.48 | 3.7E-11 | Height |
| THYM | cis | rs10935120 | 1 | rs4334685 | chr3:134304335 | CEP63 | chr3:134204575-134293852:+ | 0.43 | 6.36 | 7.09E-9 | Height |
| THYM | cis | rs9902453 | 1 | rs4350617 | chr17:28423088 | EFCAB5 | chr17:28256874-28435469:+ | 0.31 | 4.23 | 5.4E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs6540731 | 1 | rs4362041 | chr1:212400469 | NEK2 | chr1:211836115-211848967:- | -0.17 | -4.53 | 1.74E-5 | Intelligence (childhood) |
| THYM | cis | rs9457247 | 1 | rs436707 | chr6:167388843 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |